Xylazine-induced ex copula ejaculation in stallions. Academic Article uri icon

abstract

  • This study is a part of ongoing work toward developing pharmacological methods of enhancing and inducing ejaculation in stallions with ejaculatory dysfunction. We evaluated ex copula ejaculatory response to treatment with the alpha-adrenergic agonist xylazine hydrochloride, with and without preliminary sexual stimulation. Twenty-eight mature stallions each received, in random order, one xylazine trial (0.3 mg/lb, i.v.) without preliminary sexual stimulation, one xylazine trial with 5 to 10 min of sexual prestimulation, and one control trial (equivalent volume sterile water injection). Trials were conducted in the animal stalls. Ejaculation occurred in 15 of 56 (27%) xylazine trials. No ejaculations occurred in the sterile water control trials. In trials with sexual prestimulation, ejaculation occurred in 39% compared with 14% in trials without prestimulation. This difference was significant (P<0.05). Xylazine-induced ejaculates were collected into a plastic bag attached to a girth and were similar to those obtained by artificial vagina. Nine of the 15 ejaculations occurred within 2 min of injection.

published proceedings

  • Theriogenology

altmetric score

  • 1.25

author list (cited authors)

  • McDonnell, S. M., & Love, C. C.

citation count

  • 30

complete list of authors

  • McDonnell, SM||Love, CC

publication date

  • January 1991