Hypocalcemia following surgical treatment of metastatic anal sac adenocarcinoma in a dog. Academic Article

abstract

• A 9 yr old neutered male mixed-breed dog was presented for an anal sac apocrine gland adenocarcinoma with regional nodal metastases. At presentation, ionized calcium was 1.91 mmol/L (NOVA Stat reference range, 1.1-1.3 mmol/L). Surgical excision of the primary tumor and metastatic lymph nodes was performed. Following surgery, symptomatic hypocalcemia was noted. Repeated ionized calcium measurements confirmed hypocalcemia, and hypercalcemia of malignancy panels suggested parathyroid gland suppression as the cause. The calcium normalized with parenteral calcium administration, but calcium later became elevated with tumor recurrence and an increase in the parathormone-related peptide. Disrupted calcium homeostasis is a potential complication following the treatment of long-standing humoral hypercalcemia of malignancy.

authors

• Cornell, Karen

published proceedings

• J Am Anim Hosp Assoc

author list (cited authors)

• Saba, C., Ellis, A., & Cornell, K.

citation count

• 5

complete list of authors

• Saba, Corey||Ellis, Angela||Cornell, Karen

publication date

• November 2011

publisher

• American Animal Hospital Association  Publisher

published in

• Journal of the American Animal Hospital Association  Journal

keywords

• Adenocarcinoma
• Anal Gland Neoplasms
• Anal Sacs
• Animals
• Dog Diseases
• Dogs
• Hypocalcemia
• Male
• Neoplasm Metastasis
• Postoperative Complications

PubMed Central ID

• 22058367

Digital Object Identifier (DOI)

• 10.5326/JAAHA-MS-5601

start page

• e173

end page

• e177

volume

• 47

issue

• 6