Evaluation of a point-of-care blood glucose monitor in healthy goats.
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OBJECTIVE: To assess agreement between a point-of-care glucometer (POCG) and a laboratory chemistry analyzer for blood glucose measurements in goats. DESIGN: Prospective study. SETTING: University teaching hospital. ANIMALS: Eighteen healthy adult goats. INVESTIGATIONS: Whole blood samples were obtained via jugular venipuncture prior to premedication with xylazine and butorphanol (T0), following premedication (T20), and after 1 hour of inhalant anesthesia (T60). Each sample was tested with a POCG and a laboratory analyzer (HITA). Agreement was assessed using concordance correlation coefficients and calculation of bias and 95% limits of agreement. MEASUREMENTS AND MAIN RESULTS: Mean blood glucose concentration at T0 was 3.90.6mmol/L (7010mg/dL; POCG) and 2.90.4mmol/dL (538mg/dL; HITA). Glucose concentrations at T20 were 6.72.4mmol/L (12143mg/dL) and 5.42.1mmol/L (9737mg/dL) and at T60 were 5.71.7mmol/L (10231mg/dL) and 4.71.3mmol/L (8524mg/dL) when measured with the POCG and HITA, respectively. The POCG overestimated blood glucose compared to the HITA. The biasSD was 1.080.53mmol/L (19.49.5mg/dL) (95% LOA 0.04 to 2.11mmol/L [0.7 to 38.0mg/dL]) and the concordance correlation coefficient was 0.82. After correcting the results of the POCG using a mixed-effects linear model, the bias was 0.00.38mmol/L (0.06.8mg/dL) (95% LOA 0.74mmol/L [13.4mg/dL]) and the concordance correlation coefficient was 0.98. CONCLUSIONS: The POCG overestimated blood glucose concentrations in goats, compared to the HITA, but when the POCG concentrations were corrected, the agreement was excellent.
