Transvaginal fast-scanning optical-resolution photoacoustic endoscopy. Academic Article uri icon


  • Photoacoustic endoscopy offers in vivo examination of the visceral tissue using endogenous contrast, but its typical B-scan rate is 10Hz, restricted by the speed of the scanning unit and the laser pulse repetition rate. Here, we present a transvaginal fast-scanning optical-resolution photoacoustic endoscope with a 250-Hz B-scan rate over a 3-mm scanning range. Using this modality, we not only illustrated the morphological differences of vasculatures among the human ectocervix, uterine body, and sublingual mucosa but also showed the longitudinal and cross-sectional differences of cervical vasculatures in pregnant women. This technology is promising for screening the visceral pathological changes associated with angiogenesis.

published proceedings

  • J Biomed Opt

author list (cited authors)

  • Qu, Y., Li, C., Shi, J., Chen, R., Xu, S., Rafsanjani, H., ... Wang, L. V.

citation count

  • 31

complete list of authors

  • Qu, Yuan||Li, Chiye||Shi, Junhui||Chen, Ruimin||Xu, Song||Rafsanjani, Hasan||Maslov, Konstantin||Krigman, Hannah||Garvey, Laura||Hu, Peng||Zhao, Peinan||Meyers, Karen||Diveley, Emily||Pizzella, Stephanie||Muench, Lisa||Punyamurthy, Nina||Goldstein, Naomi||Onwumere, Oji||Alisio, Mariana||Meyenburg, Kaytelyn||Maynard, Jennifer||Helm, Kristi||Slaughter, Janessia||Barber, Sabrina||Burger, Tracy||Kramer, Christine||Chubiz, Jessica||Anderson, Monica||McCarthy, Ronald||England, Sarah K||Macones, George A||Zhou, Qifa||Shung, K Kirk||Zou, Jun||Stout, Molly J||Tuuli, Methodius||Wang, Lihong V

publication date

  • December 2018