Transvaginal fast-scanning optical-resolution photoacoustic endoscopy Academic Article uri icon


  • Photoacoustic endoscopy offers in vivo examination of the visceral tissue using endogenous contrast, but its typical B-scan rate is ∼10  Hz, restricted by the speed of the scanning unit and the laser pulse repetition rate. Here, we present a transvaginal fast-scanning optical-resolution photoacoustic endoscope with a 250-Hz B-scan rate over a 3-mm scanning range. Using this modality, we not only illustrated the morphological differences of vasculatures among the human ectocervix, uterine body, and sublingual mucosa but also showed the longitudinal and cross-sectional differences of cervical vasculatures in pregnant women. This technology is promising for screening the visceral pathological changes associated with angiogenesis.

author list (cited authors)

  • Qu, Y., Li, C., Shi, J., Chen, R., Xu, S., Rafsanjani, H., ... Wang, L. V.

citation count

  • 16

publication date

  • December 2018