Perceived stress in prodromal Huntington disease. Academic Article

abstract

• This study examines perceived stress and its relationship to depressive symptoms, life changes and functional capacity in a large sample of individuals who are positive for the Huntington disease (HD) gene expansion but not yet diagnosed. Participants were classified by estimated proximity to HD diagnosis (far, mid, near) and compared with a non-gene-expanded comparison group. Persons in the mid group had the highest stress scores. A significant interaction between age and time since HD genetic testing was also found. Secondary analyses using data from a different data collection point and including a diagnosed group showed the highest stress scores in the diagnosed group. Possible explanations and implications are discussed.

authors

• Downing, Nancy

published proceedings

• Psychol Health

author list (cited authors)

• Downing, N., Smith, M. M., Beglinger, L. J., Mills, J., Duff, K., Rowe, K. C., ... PREDICT-HD Investigators of Huntington Study Group.

citation count

• 21

complete list of authors

• Downing, Nancy||Smith, Megan M||Beglinger, Leigh J||Mills, James||Duff, Kevin||Rowe, Kelly C||Epping, Eric||Paulsen, Jane S

publication date

• February 2012

publisher

• Taylor & Francis  Publisher

published in

• Psychology and Health: an international journal  Journal

keywords

• Adult
• Depression
• Female
• Genetic Predisposition To Disease
• Humans
• Huntington Disease
• Longitudinal Studies
• Male
• Middle Aged
• Self Report
• Stress, Psychological
• Young Adult

PubMed Central ID

• 21623544

Digital Object Identifier (DOI)

• 10.1080/08870446.2010.529141

start page

• 196

end page

• 209

volume

• 27

issue

• 2

URL

• http://dx.doi.org/10.1080/08870446.2010.529141