Virally encoded microRNA (miRNA): Candidates for gene silencing Chapter uri icon

abstract

  • © 2009 by Taylor & Francis Group, LLC. MicroRNAs (miRNAs) are small noncoding RNAs regulating gene expression through mRNA degradation or translation inhibition [1-3]. MicroRNAs were first discovered in the nematode, Caenorhabditis elegans, and then identified in numerous plant and animal species [2, 4-7]. A miRNA is defined as a single-stranded RNA 19-25 nucleotides (nt) in length generated from endogenous transcripts that form local hairpin structures [1, 8, 9]. The majority of miRNA genes are located.

author list (cited authors)

  • Tripp, R. A., Rogovskyy, A. S., Jones, L. P., & Tompkins, S. M.

citation count

  • 0

Book Title

  • Gene Profiles in Drug Design

publication date

  • January 2008