Light scattering by pulmonary alveoli and airway surface liquid using a concentric sphere model. Academic Article

abstract

• We employ a concentric sphere Mie scattering model to describe light scattering by pulmonary alveoli and airway surface liquid (ASL). Using this layered sphere model, we compare alveolar scattering at different points along the respiratory cycle and observe the effect of ASL thickness on light scattering in the lung. We have also extrapolated the model to investigate alveolar scattering in various animal models of pulmonary disease. This model of pulmonary light scattering can estimate in vivo optical properties for normal and pathological states, potentially aiding the design of optical systems for diagnosis and investigation of pulmonary pathologies.

authors

• Cirillo, Jeffrey
• Maitland, Duncan

published proceedings

• Opt Lett

author list (cited authors)

• Durkee, M. S., Fletcher, G. K., Carlson, C., Matheson, K., Swift, S. K., Maitland, D. J., Cirillo, J. D., & Maitland, K. C.

citation count

• 4

complete list of authors

• Durkee, Madeleine S||Fletcher, Grace K||Carlson, Camella||Matheson, Kanci||Swift, Sarah K||Maitland, Duncan J||Cirillo, Jeffrey D||Maitland, Kristen C

publication date

• October 2018

publisher

• Optica Publishing Group  Publisher

published in

• Optics Letters  Journal

keywords

• 40 Engineering
• 4018 Nanotechnology
• Lung
• Rare Diseases
• Respiratory

PubMed Central ID

• 30320804

Digital Object Identifier (DOI)

• 10.1364/OL.43.005001

start page

• 5001

end page

• 5004

volume

• 43

issue

• 20

URL

• http://dx.doi.org/10.1364/ol.43.005001