The Oral Fluid MEMS/NEMS Chip (OFMNC): Diagnostic & Translational Applications Academic Article uri icon


  • The ability to monitor health status, disease onset and progression, and treatment outcome through non-invasive means is a most desirable goal in health-care promotion and delivery. There are three prerequisites for this goal to be realized: specific biomarkers associated with a health or disease state, a non-invasive approach to detect and monitor the biomarkers, and the technologies to discriminate between and among the biomarkers. We present a roadmap to achieve these goals using oral fluids as the diagnostic medium to scrutinize the health and/or disease status of individuals. This is an ideal opportunity to bridge state-of-the-art micro-/nano-electromechanical system (MEMS/NEMS) sensors to oral fluid for diagnostic applications. As the "mirror of body", oral fluid is a perfect medium to be explored for health and disease surveillance. The translational applications and opportunities are enormous.

altmetric score

  • 3

author list (cited authors)

  • Li, Y., Denny, P., Ho, C., Montemagno, C., Shi, W., Qi, F., ... Wong, D. T.

citation count

  • 48

publication date

  • June 2005