The role of bacterial-laden biofilms in infections of maxillofacial biomaterials. Academic Article uri icon


  • Biomaterials from 11 consecutive patients with persistent infections refractory to antimicrobial therapy and local wound care were surgically removed and studied by scanning electron microscopy for the presence of bacterial-laden biofilms. Unlike previously reported biomaterial infections involving other regions of the body, infections in this study were not associated with a conspicuous bacterial-laden biofilm. Instead, adherent light bacterial colonization without a biofilm layer was noted. The only specimen that was suggestive of a bacterial-laden biofilm was in a patient who suffered from a chronic infection. Consistent with previous reports, bacterial colonization was frequently polymicrobial. Observations made in this study suggest that bacterial adherence may not require an obvious biofilm layer.

published proceedings

  • J Oral Maxillofac Surg

author list (cited authors)

  • Nishioka, G. J., Jones, J. K., Triplett, R. G., & Aufdemorte, T. B.

citation count

  • 15

complete list of authors

  • Nishioka, GJ||Jones, JK||Triplett, RG||Aufdemorte, TB

publication date

  • January 1988