Effect of preoperative cimetidine and ranitidine on gastric secretion.
Academic Article
Overview
Research
Identity
Additional Document Info
Other
View All
Overview
abstract
To decrease gastric volume and acidity prior to anesthesia and surgery and decrease the risk of aspiration, a prospective double-blind trial comparing two H2 receptor blockers, cimetidine and ranitidine, was performed. Analysis of gastric contents revealed both drugs to be extremely effective in raising gastric pH to the 6-7 range. However, ranitidine was shown to be more effective in decreasing gastric volume.