Experimental mandibular osteomyelitis: therapeutic trials with hyperbaric oxygen. Academic Article

abstract

• Hyperbaric oxygen (HBO) has been reported to be beneficial in the treatment of mandibular osteomyelitis; however, controlled laboratory studies have been limited to the long bones. In this study, osteomyelitis was created in surgically fractured rabbit mandibles by inoculation of Bacteroides melaninogenicus. Two months after inoculation, osteomyelitis was verified by bacterial cultures and inspection of the fracture sites. The animals were then randomly divided into treatment and control groups. The treatment group received HBO (2 atmospheres) for two hours daily for 40 treatment days, whereas the control group was maintained on ambient air. Although HBO therapy did not eliminate the chronic osteomyelitis, it did result in a significant improvement in sinus tract healing, osseous repair, and diminished mobility at the fracture site.

authors

• Triplett, Robert

published proceedings

• J Oral Maxillofac Surg

author list (cited authors)

• Triplett, R. G., Branham, G. B., Gillmore, J. D., & Lorber, M.

citation count

• 23

complete list of authors

• Triplett, RG||Branham, GB||Gillmore, JD||Lorber, M

publication date

• January 1982

publisher

• Elsevier  Publisher

published in

• Journal of Oral and Maxillofacial Surgery  Journal

keywords

• Animals
• Bacteroides Infections
• Hyperbaric Oxygenation
• Male
• Mandibular Diseases
• Osteogenesis
• Osteomyelitis
• Rabbits
• Research Design
• Time Factors

PubMed Central ID

• 6956686

Digital Object Identifier (DOI)

• 10.1016/0278-2391(82)90113-6

start page

• 640

end page

• 646

volume

• 40

issue

• 10

URL

• http://dx.doi.org/10.1016/0278-2391(82)90113-6