Effects of turbulent velocity fluctuations upon computationally simulated magnetic resonance angiograms Conference Paper uri icon

abstract

  • Magnetic resonance time-of-flight angiography is currently limited in the evaluation of arterial diseases by the signal loss which occurs with flow through stenoses. This signal loss has been attributed to phase dispersion and to phase misregistration. The current study used computational simulations of 2D time-of-flight MR angiograms to examine signal loss distal to a stenosis. The results indicated that turbulent phase dispersion (range of phase within a pixel due to turbulent motion) was the dominant mechanism of signal loss, while phase misregistration and mean flow phase dispersion acted as secondary effects. The computational simulations of turbulent intravoxel signal loss can be significantly turbulent intravoxel signal loss can be significantly reduced through low echo time, high gradient slew rate periodic waveforms.

published proceedings

  • American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

author list (cited authors)

  • Siegel, J. M., Oshinski, J. N., Pettigrew, R. I., & Ku, D. N.

complete list of authors

  • Siegel, JM||Oshinski, JN||Pettigrew, RI||Ku, DN

publication date

  • January 1995