Coronary abnormalities in hyper-IgE recurrent infection syndrome: depiction at coronary MDCT angiography. Academic Article

abstract

• OBJECTIVE: Hyper-IgE recurrent infection syndrome (HIES or Job's syndrome) is a rare disorder affecting the immune system and connective tissues. The purpose of this study is to describe the coronary abnormalities in genetically confirmed HIES patients as depicted by coronary MDCT angiography (MDCTA). CONCLUSION: Coronary MDCTA has provided an opportunity for noninvasive evaluation of the coronary arteries in patients with HIES. These coronary abnormalities vary from tortuosity to ectatic dilation and focal aneurysms of the coronary arteries. Such an evaluation has potential value in identifying new aspects of this disease and thereby providing better understanding of the pathophysiology of the disorder.

authors

• Pettigrew, Roderic

published proceedings

• AJR Am J Roentgenol

author list (cited authors)

• Gharib, A. M., Pettigrew, R. I., Elagha, A., Hsu, A., Welch, P., Holland, S. M., & Freeman, A. F.

citation count

• 18

complete list of authors

• Gharib, Ahmed M||Pettigrew, Roderic I||Elagha, Abdalla||Hsu, Amy||Welch, Pam||Holland, Steven M||Freeman, Alexandra F

publication date

• December 2009

publisher

• American Roentgen Ray Society  Publisher

published in

• American Journal of Roentgenology  Journal

keywords

• Adult
• Contrast Media
• Coronary Angiography
• Coronary Disease
• Diagnosis, Differential
• Female
• Humans
• Imaging, Three-Dimensional
• Immunoglobulin E
• Iopamidol
• Job Syndrome
• Male
• Middle Aged
• Radiographic Image Interpretation, Computer-Assisted
• Recurrence
• Tomography, X-Ray Computed

Digital Object Identifier (DOI)

• 10.2214/AJR.09.2623

start page

• W478

end page

• W481

volume

• 193

issue

• 6

URL

• http://dx.doi.org/10.2214/ajr.09.2623