Reactivity studies of anticancer active dirhodium complexes with 2-aminothiophenol. Academic Article

abstract

• Reactions between the antitumor active compound [Rh2II,II (-O2CCH3)2(phen)2 (CH3CN)2][PF6]2 (phen = l, 10-phenanthroline) and excess 2-aminothiophenol in the presence of oxygen yields The neutral complex [RhIII(n2C6H6NS) (n1-C6H6NS)2(phen)] (2), which was characterized by spectroscopic and crystallographic methods. Dinuclear intermediates are most likely involved in this chemistry as indicated by the isolation of [Rh2III.III (-C6H6NS)2 (C6H6NS)2(bpy)2]2+ (3a) as well as [RhIII(C6H6NS)2- (bpy)]+ (3b) from reactions of Rh2II.II (-O2CCH3)2(bpy)2- (CH3CN)2 with 4 equiv of 2-aminothiophenol.

authors

• Dunbar, Kim

published proceedings

• Inorg Chem

author list (cited authors)

• Sorasaenee, K., Galn-Mascars, J. R., & Dunbar, K. R.

citation count

• 32

complete list of authors

• Sorasaenee, Karn||Galán-Mascarós, José Ramón||Dunbar, Kim R

publication date

• January 2002

publisher

• American Chemical Society (ACS)  Publisher

published in

• Inorganic Chemistry  Journal

keywords

• Aniline Compounds
• Antineoplastic Agents
• Crystallography, X-Ray
• Cysteine
• Glutathione
• Magnetic Resonance Spectroscopy
• Models, Chemical
• Molecular Conformation
• Molecular Structure
• Organometallic Compounds
• Organoplatinum Compounds
• Rhodium
• Spectroscopy, Fourier Transform Infrared
• Sulfhydryl Compounds

PubMed Central ID

• 11800637

Digital Object Identifier (DOI)

• 10.1021/ic010799v

start page

• 433

end page

• 436

volume

• 41

issue

• 2

URL

• http://dx.doi.org/10.1021/ic010799v