Noninvasive detection of colonic biomarkers using fecal messenger RNA Patent uri icon


  • A noninvasive method utilizing feces, containing sloughed colonocytes, as a sensitive technique for detecting diagnostic colonic biomarkers as well as a method for isolating poly A +RNA from feces. The method allows the isolation and quantitation of specific eukarotic mRNAs as candidate biomarkers for colon cancer isolated from feces.

author list (cited authors)

  • Chapkin, R., Davidson, L., & Lupton, J.

complete list of authors

  • Chapkin, Robert||Davidson, Laurie||Lupton, Joanne

publication date

  • July 2001