New functions for DNA modifications by TET-JBP. Academic Article

abstract

• TET and JBP proteins catalyze the oxidation of methylated C bases in the mammalian genome and of the methyl group of T bases in kinetoplastid genomes, respectively. A recent study in Nature Structural & Molecular Biology suggests a new function of 5-methylcytosine oxidation in regulating RNA polymerase II elongation rate that is reminiscent of that of base J in transcription termination in Leishmania.

authors

• Huang, Yun

published proceedings

• Nat Struct Mol Biol

altmetric score

• 1.25

author list (cited authors)

• Huang, Y., & Rao, A.

citation count

• 9

complete list of authors

• Huang, Yun||Rao, Anjana

publication date

• January 2012

publisher

• Springer Nature  Publisher

published in

• Nature Structural and Molecular Biology  Journal

keywords

• Cytosine
• Humans
• RNA Polymerase II

Digital Object Identifier (DOI)

• 10.1038/nsmb.2437

start page

• 1061

end page

• 1064

volume

• 19

issue

• 11

URL

• http://dx.doi.org/10.1038/nsmb.2437

user-defined tag

• 3 Good Health and Well-Being