Zirconium phosphate nano-platelets: a novel platform for drug delivery in cancer therapy Academic Article uri icon

abstract

  • Doxorubicin was intercalated into novel zirconium phosphate nano-platelets (ZrP). The obtained doxorubicin intercalated ZrP nano-platelets had an impressive 34.9% (w/w) drug loading. We used this material to deliver doxorubicin to breast cancer cells (MCF-7). Cellular studies with MCF-7 cells showed higher uptake and cytotoxicity of doxorubicin loaded ZrP compared to free doxorubicin.

altmetric score

  • 3

author list (cited authors)

  • Díaz, A., Saxena, V., González, J., David, A., Casañas, B., Carpenter, C., ... Hussain, M. D.

citation count

  • 100

publication date

  • January 2012