Zirconium phosphate nano-platelets: a novel platform for drug delivery in cancer therapy
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Doxorubicin was intercalated into novel zirconium phosphate nano-platelets (ZrP). The obtained doxorubicin intercalated ZrP nano-platelets had an impressive 34.9% (w/w) drug loading. We used this material to deliver doxorubicin to breast cancer cells (MCF-7). Cellular studies with MCF-7 cells showed higher uptake and cytotoxicity of doxorubicin loaded ZrP compared to free doxorubicin.
author list (cited authors)
Díaz, A., Saxena, V., González, J., David, A., Casañas, B., Carpenter, C., ... Hussain, M. D.