IMPLICATIONS OF SENSE/ANTISENSE NUCLEIC-ACID CODONS ON AMINO-ACID COUNTS Academic Article

abstract

• We study the amino-acid content of protein sequence factors translated from codonic palindromes of nucleotide sequences, which have each half comprised from an integer number of codons. Alternatively, our study may be viewed to seek consequences if sense & antisense translations for proteins originate with the two (complementary) strands of RNA. Under either of these presuppositions, we conclude: the total number of aspartic-acid, asparagine, tyrosine, and histidine residues produced equals the total number of isoleucine, methionine, and valine residues produced. Further, we find a suite of inequalities on amino acid counts. Our results provide a rigorous consequence to a relation considered by Zull et al. Further, a "parity rule" of Chargaff et al. gives some support for a sense/antisense presumption.

authors

• Klein, Douglas

published proceedings

• STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA

author list (cited authors)

• Rosenfeld, V. R., & Klein, D. J.

complete list of authors

• Rosenfeld, Vladimir R||Klein, Douglas J

publication date

• December 2010

published in

• Studia Universitatis Babes-Bolyai Chemia  Journal

keywords

• Codonic Palindrome
• Complementation
• Nucleotide Sequence
• Parity Rule
• Translation

start page

• 167

end page

• 176

volume

• 55

issue

• 4