Intermolecular Ritter-type C-H amination of unactivated sp3 carbons. Academic Article

abstract

• Intermolecular Ritter-type C-H amination of unactivated sp(3) carbons has been developed. This new reaction proceeds under mild conditions using readily available reagents and an inexpensive source of nitrogen (acetonitrile). A broad scope of substrates can be aminated with this method since many functional groups are tolerated. This reaction also allows for the direct, innate C-H amination of a variety of hydrocarbons such as cyclohexane without the need of prefunctionalization or installation of a directing group.

authors

• Michaudel, Quentin

published proceedings

• J Am Chem Soc

altmetric score

• 20.274

author list (cited authors)

• Michaudel, Q., Thevenet, D., & Baran, P. S.

citation count

• 231

complete list of authors

• Michaudel, Quentin||Thevenet, Damien||Baran, Phil S

publication date

• February 2012

publisher

• American Chemical Society (ACS)  Publisher

published in

• Journal of the American Chemical Society  Journal

keywords

• Alcohols
• Amides
• Amination
• Amines
• Hydrocarbons
• Ketones
• Molecular Structure
• Stereoisomerism

PubMed Central ID

• 22276612

Digital Object Identifier (DOI)

• 10.1021/ja212020b

start page

• 2547

end page

• 2550

volume

• 134

issue

• 5

URL

• http://dx.doi.org/10.1021/ja212020b