Early stress response: a vulnerability framework for functional impairment following mild traumatic brain injury.

abstract

• Nearly 64% of people with mild traumatic brain injury (MTBI) experience prolonged symptoms and functional impairments lasting months or years postinjury. Explanations for delayed recovery have varied and lacked a guiding framework, hindering intervention science. Using theory substruction and adapting McLean and associates' biopsychosocial model for chronic pain after trauma, we suggest that perceived psychological stress and associated neurobiological responses may predict risk for functional impairment. This model can be tested using a biopsychosocial approach to determine the interplay of psychological stress and neurobiological responses implicated in functional impairments after MTBI. Testing of this model will advance understanding of pathways to postconcussion syndrome.

authors

• Liberzon, Israel

published proceedings

• Res Theory Nurs Pract

author list (cited authors)

• Bay, E. H., & Liberzon, I.

citation count

• 18

complete list of authors

• Bay, Esther H||Liberzon, Israel

publication date

• February 2009

publisher

• Springer Publishing Company  Publisher

published in

• n1541-6577ISSN  Journal

keywords

• Adrenal Glands
• Autonomic Nervous System
• Brain Injuries
• Humans
• Hydrocortisone
• Hypothalamo-Hypophyseal System
• Models, Biological
• Models, Nursing
• Models, Psychological
• Nurse's Role
• Pain
• Pituitary Gland
• Post-concussion Syndrome
• Recovery Of Function
• Rehabilitation Nursing
• Risk Assessment
• Risk Factors
• Stress Disorders, Post-Traumatic

PubMed Central ID

• 19418887

Digital Object Identifier (DOI)

• 10.1891/1541-6577.23.1.42

start page

• 42

end page

• 61

volume

• 23

issue

• 1

URL

• http://dx.doi.org/10.1891/1541-6577.23.1.42

user-defined tag

• 3 Good Health and Well-Being