Observation of a Photogenerated Rh2 Nitrenoid Intermediate in C-H Amination. Academic Article uri icon

abstract

  • Rh2-catalyzed C-H amination is a powerful method for nitrogenating organic molecules. While Rh2 nitrenoids are often invoked as reactive intermediates in these reactions, the exquisite reactivity and fleeting lifetime of these species has precluded their observation. Here, we report the photogeneration of a transient Rh2 nitrenoid that participates in C-H amination. The developed approach to Rh2 nitrenoids, based on photochemical cleavage of N-Cl bonds in N-chloroamido ligands, has enabled characterization of a reactive Rh2 nitrenoid by mass spectrometry and transient absorption spectroscopy. We anticipate that photogeneration of metal nitrenoids will contribute to the development of C-H amination catalysis by providing tools to directly study the structures of these critical intermediates.

published proceedings

  • J Am Chem Soc

altmetric score

  • 1

author list (cited authors)

  • Das, A., Maher, A. G., Telser, J., & Powers, D. C.

citation count

  • 23

complete list of authors

  • Das, Anuvab||Maher, Andrew G||Telser, Joshua||Powers, David C

publication date

  • August 2018