Towards a systematic framework for the synthesis of operable process intensification systems Chapter uri icon


  • 2018 Elsevier B.V. In this work we present an integrated framework to derive intensified designs with guaranteed safety and operability performance. A step-by-step procedure is described featuring: (i) superstructure-based process synthesis using Generalized Modular Representation Framework, (ii) development of advanced multi-parametric control strategies following the PAROC framework and software platform, and (iii) inherent safety analysis at early design stage utilizing quantitative risk assessment. Two case studies with increasing intensification complexity, namely heat exchanger network synthesis and reactive distillation column design, are investigated to demonstrate the capabilities of the proposed framework.

author list (cited authors)

  • Tian, Y., Mannan, M. S., & Pistikopoulos, E. N.

citation count

  • 10

complete list of authors

  • Tian, Yuhe||Mannan, M Sam||Pistikopoulos, Efstratios N

Book Title

  • 13th International Symposium on Process Systems Engineering (PSE 2018)

publication date

  • January 2018