Permeation of genistein through human skin Academic Article

abstract

• The authors investigated the transdermal permeation efficiency of genistein through abdominal human cadaver skin and the effect of permeation enhancers dimethylformamide (DMF), dimethylsulfoxide (DMSO), olive oil, and alcohol on the permeation efficiency of genistein. Permeation parameters such as the flux and permeability coefficients were determined. DMF, DMSO, and olive oil (5% v/v) provided enhanced permeation when the concentration of genistein was 10 mg/mL. Alcohol (5% v/v) failed to provide any permeation enhancement of genistein. No genistein permeation was observed without enhancer.

authors

• Khan, Mansoor
• Reddy, Indra

published proceedings

• Pharmaceutical Technology

author list (cited authors)

• Motlekar, N. A., Shah, R. B., Reddy, I. K., Keller, W. J., & Khan, M. A.

complete list of authors

• Motlekar, NA||Shah, RB||Reddy, IK||Keller, WJ||Khan, MA

publication date

• March 2003

published in

• Pharmaceutical Technology  Journal

start page

• 140

end page

• 148

volume

• 27

issue

• 3