Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review Academic Article uri icon

abstract

  • 2015 American Chemical Society. This multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based process monitoring and control methods) and presenting applications both in industrial laboratories and in manufacture e.g. at GSK, AstraZeneca and Roche. Furthermore, the paper discusses the PAT paradigm from the regulatory science perspective. Given the multidisciplinary nature of PAT, such an endeavour would be almost impossible for a single author, so the concept of a multiauthor review was born. Each section of the multiauthor review has been written by a single expert or group of experts with the aim to report on its own research results. This paper also serves as a comprehensive source of information on PAT topics for the novice reader.

published proceedings

  • Organic Process Research & Development

altmetric score

  • 3.1

author list (cited authors)

  • Simon, L. L., Pataki, H., Marosi, G., Meemken, F., Hungerbuhler, K., Baiker, A., ... Chiu, M.

citation count

  • 285

complete list of authors

  • Simon, Levente L||Pataki, Hajnalka||Marosi, György||Meemken, Fabian||Hungerbühler, Konrad||Baiker, Alfons||Tummala, Srinivas||Glennon, Brian||Kuentz, Martin||Steele, Gerry||Kramer, Herman JM||Rydzak, James W||Chen, Zengping||Morris, Julian||Kjell, Francois||Singh, Ravendra||Gani, Rafiqul||Gernaey, Krist V||Louhi-Kultanen, Marjatta||O’Reilly, John||Sandler, Niklas||Antikainen, Osmo||Yliruusi, Jouko||Frohberg, Patrick||Ulrich, Joachim||Braatz, Richard D||Leyssens, Tom||von Stosch, Moritz||Oliveira, Rui||Tan, Reginald BH||Wu, Huiquan||Khan, Mansoor||O’Grady, Des||Pandey, Anjan||Westra, Remko||Delle-Case, Emmanuel||Pape, Detlef||Angelosante, Daniele||Maret, Yannick||Steiger, Olivier||Lenner, Miklós||Abbou-Oucherif, Kaoutar||Nagy, Zoltan K||Litster, James D||Kamaraju, Vamsi Krishna||Chiu, Min-Sen

publication date

  • January 2015