Resin effects in solid phase S(n)Ar and S(n)2 macrocyclizations. Academic Article

abstract

• Seven different supports were compared in solid-phase S(N)Ar and S(N)2 macrocyclization reactions. Product purities were assayed for a relatively facile ring-closure process to give products 1 and 3. Some less-facile ring-closure reactions give the undesired dimeric macrocyclization by-products 2; some of these more-demanding ring closures were also examined. Finally, experiments were performed to gauge the rate of cyclizations on different resins, and some qualitative data were obtained for this.

authors

• Burgess, Kevin

published proceedings

• Biotechnol Bioeng

altmetric score

• 3

author list (cited authors)

• Feng, Y., & Burgess, K.

citation count

• 14

complete list of authors

• Feng, Y||Burgess, K

publication date

• December 2000

publisher

• Wiley  Publisher

keywords

• Dimerization
• Hydrocarbons, Cyclic
• Indicators And Reagents
• Molecular Structure
• Polystyrenes
• Resins, Plant

Digital Object Identifier (DOI)

• 10.1002/(sici)1097-0290(200024)71:1<3::aid-bit2>3.0.co;2-k

start page

• 3

end page

• 8

volume

• 71

issue

• 1

URL

• http://dx.doi.org/10.1002/(sici)1097-0290(200024)71:1%3C3::aid-bit2%3E3.0.co;2-k