Selective formation of homo- and heterobivalent peptidomimetics. Academic Article

abstract

• Methodology is presented for assembling fluorescently labeled bivalent molecules from monovalent constituents, without side chain protection or coupling agents. To illustrate the procedure, a series of bivalent peptidomimetics directed toward the Trk receptors were prepared and screened via fluorescent activated cell sorting scan assays.

authors

• Burgess, Kevin

published proceedings

• J Med Chem

altmetric score

• 3

author list (cited authors)

• Pattarawarapan, M., Reyes, S., Xia, Z., Zaccaro, M. C., Saragovi, H. U., & Burgess, K.

citation count

• 15

complete list of authors

• Pattarawarapan, Mookda||Reyes, Samuel||Xia, Zebin||Zaccaro, Maria C||Saragovi, H Uri||Burgess, Kevin

publication date

• August 2003

publisher

• American Chemical Society (ACS)  Publisher

published in

• Journal of Medicinal Chemistry  Journal

keywords

• Amino Acids
• Carrier Proteins
• Cell Line
• Combinatorial Chemistry Techniques
• Dimerization
• Flow Cytometry
• Fluorescent Dyes
• Heterocyclic Compounds, 2-ring
• Membrane Proteins
• Molecular Mimicry
• Nerve Growth Factors
• Peptides
• Receptor, TrkA
• Receptor, Trkc

PubMed Central ID

• 12904060

Digital Object Identifier (DOI)

• 10.1021/jm034103e

start page

• 3565

end page

• 3567

volume

• 46

issue

• 17