On formation of thiohydantoins from amino acids under acylation conditions. Academic Article uri icon


  • Reactions of glycine, alanine, and phenylalanine with acetic anhydride and ammonium thiocyanate give the 1-acetyl-2-thiohydantoins 2a-c. These results appear to contradict prior literature reports pertaining to this reaction.

published proceedings

  • J Org Chem

author list (cited authors)

  • Reyes, S., & Burgess, K.

citation count

  • 39

complete list of authors

  • Reyes, Samuel||Burgess, Kevin

publication date

  • March 2006