α,ω‐Functionalized 2,4‐Dimethylpentane Dyads and 2,4,6‐Trimethylheptane Triads through Asymmetric Hydrogenation Academic Article uri icon

abstract

  • A match made in heaven: All the possible stereoisomers of α,ω-functionalized 2,4-dimethylpentane dyad and 2,4,6-tri- methylheptane triad chirons (see picture; A and B, respectively; FG = functional group, PG = protecting group) can be reached by using a combination of a chiral catalyst and substrate effects in the hydrogenation of mainly nonfunctionalized alkenes. Excellent diastereo- and enantioselectivities were achieved. (Chemical Equation Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

altmetric score

  • 3

author list (cited authors)

  • Zhou, J., & Burgess, K.

citation count

  • 70

publication date

  • February 2007

publisher