Alpha,omega-functionalized 2,4-dimethylpentane dyads and 2,4,6-trimethylheptane triads through asymmetric hydrogenation. Academic Article uri icon


  • A match made in heaven: All the possible stereoisomers of ,-functionalized 2,4-dimethylpentane dyad and 2,4,6-tri- methylheptane triad chirons (see picture; A and B, respectively; FG = functional group, PG = protecting group) can be reached by using a combination of a chiral catalyst and substrate effects in the hydrogenation of mainly nonfunctionalized alkenes. Excellent diastereo- and enantioselectivities were achieved. (Chemical Equation Presented). 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

published proceedings

  • Angew Chem Int Ed Engl

altmetric score

  • 3

author list (cited authors)

  • Zhou, J., & Burgess, K.

citation count

  • 80

complete list of authors

  • Zhou, Jianguang||Burgess, Kevin

publication date

  • February 2007