n36361SE Academic Article uri icon


  • (Chemical Equation Presented) Click, click: Using a carbonate base as an additive in the copper-accelerated click reaction of alkynes and azides led to an oxidative coupling to form predominately 5,5-bistriazoles (see scheme). The reaction proved more facile for propargylic ethers and less hindered substrates. Use of an optically active azide gave separable atropisomeric products and provides a convenient access to optically pure derivatives. 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

published proceedings

  • Angew Chem Int Ed Engl

author list (cited authors)

  • Angell, Y. u., & Burgess, K.

publication date

  • January 1, 2007 11:11 AM