BODIPY dyes and their derivatives: syntheses and spectroscopic properties.
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The 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene or BODIPY dyes are strongly UV-absorbing small molecules emitting a relatively sharp fluorescence peaks with high quantum yields. The modification of BODIPY framework will lead to probes to be used more effectively for imaging in living cells and whole organisms. In facilitating this process, a summarization of basic chemistry and spectroscopic properties of common BODIPY-derivatives was reviewed and highligting ways in which other interesting probes could be prepared. This review provides the readers particularly interested in applications of BODIPY dyes, a guide to synthesis and spectroscopic properties.