Pyrrole-based scaffolds for turn mimics. Academic Article uri icon


  • Two amino acid derived synthons were combined to give homopropargylic amines 2. Platinum dichloride was used to cyclize these intermediates into pyrroles 3 which collapsed to the target secondary structure mimics 1 on treatment with base. Side chains of these compounds overlay with an idealized type 1 -turn and with an inverse -turn.

published proceedings

  • Org Lett

altmetric score

  • 3

author list (cited authors)

  • Ko, E., & Burgess, K.

citation count

  • 24

complete list of authors

  • Ko, Eunhwa||Burgess, Kevin

publication date

  • March 2011