Towards the synthesis of modular process intensification systems with safety and operability considerations - application to heat exchanger network Chapter uri icon


  • 2018 Elsevier B.V. In this work, we present a systematic framework for the synthesis of safely operable process intensification systems. Herein, intensified designs are automatically generated by using phenomena-based Generalized Modular Representation Framework, while their safety and operability performances are guaranteed by incorporating: (i) flexibility analysis and multiperiod design, (ii) inherent safety analysis utilizing quantitative risk assessment, and (iii) multi-parametric model predictive control strategies developed via the PAROC framework. As an example from a broader set of intensified systems, the proposed framework is applied to heat exchanger network synthesis for thermal intensification, demonstrating its capability on enhancing safety and operability at early design stage.

author list (cited authors)

  • Tian, Y., Mannan, M. S., Kravanja, Z., & Pistikopoulos, E. N.

citation count

  • 8

complete list of authors

  • Tian, Yuhe||Mannan, M Sam||Kravanja, Zdravko||Pistikopoulos, Efstratios N

Book Title

  • 28th European Symposium on Computer Aided Process Engineering

publication date

  • January 2018