Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes. Academic Article

abstract

• Screening of a mouse spleen genomic DNA library with mouse BMP-4 and BMP-2 cDNA probes led to the isolation of mouse BMP-2 gene. This gene contains approximately 11 kb transcription unit and 3 exons. The deduced protein has 394 amino acids. The C-terminal amino acid mature coding region is identical to that of the human BMP-2. Comparison of mouse BMP-2 and BMP-4 gene shows little similarity in exon/intron structure, although the mature coding peptide regions of both genes share over 90% identity at the amino acid level.

authors

• Feng, Jian

published proceedings

• Biochim Biophys Acta

altmetric score

• 6

author list (cited authors)

• Feng, J. Q., Harris, M. A., Ghosh-Choudhury, N., Feng, M., Mundy, G. R., & Harris, S. E.

citation count

• 66

complete list of authors

• Feng, JQ||Harris, MA||Ghosh-Choudhury, N||Feng, M||Mundy, GR||Harris, SE

publication date

• June 1994

publisher

• Elsevier  Publisher

published in

• Biochimica et Biophysica Acta: international journal of biochemistry and biophysics  Journal

keywords

• Amino Acid Sequence
• Animals
• Base Sequence
• Bone Morphogenetic Proteins
• Growth Substances
• Mice
• Molecular Sequence Data
• Proteins
• Restriction Mapping

PubMed Central ID

• 8018727

Digital Object Identifier (DOI)

• 10.1016/0167-4781(94)90017-5

start page

• 221

end page

• 224

volume

• 1218

issue

• 2

URL

• http://dx.doi.org/10.1016/0167-4781(94)90017-5