Evaluation of the levels of oral Candida in patients with Sjgren's syndrome. Academic Article uri icon

abstract

  • OBJECTIVE: The purpose of this study was to investigate the levels of oral Candida in patients with Sjgren's syndrome METHODS: The Candida count and salivary flow rate of patients with Sjgren's syndrome were compared with those of healthy control subjects. Candida cultures were obtained from oral rinses. The numbers of colony-forming units were determined through use of the Spiral System. RESULTS: The mean Candida count of patients with Sjgren's syndrome was 1672 +/- 1455 colony-forming units per mL; the count of healthy control subjects was 0.00 colony-forming units per mL. The mean salivary flow rate of patients with Sjgren's syndrome was significantly lower than that of healthy control subjects (0.16 +/- 0.13 mL/min/gland vs 0.55 +/- 0.24 mL/min/gland, respectively; p = 0.0001). However, Spearman rank correlation analyses did not reveal a significant correlation between salivary flow rate and Candida count (in colony-forming units per mL) among patients with Sjgren's syndrome. CONCLUSIONS: Alteration in the oral microbial flora in patients with Sjgren's syndrome may be enhanced by the reduction in salivary output.

published proceedings

  • Oral Surg Oral Med Oral Pathol Oral Radiol Endod

author list (cited authors)

  • Abraham, C. M., al-Hashimi, I., & Haghighat, N.

publication date

  • January 1, 1998 11:11 AM