PC program for determining the dose necessary to produce a given amount of change. Academic Article

abstract

• Given a simple linear regression equation of the form D = alpha + beta Z, it is well-known how to predict, and construct confidence intervals for, the value of D corresponding to a given Z. In this paper we describe, illustrate and make available a menu-driven PC program which can be used to solve the inverse problem, namely, to estimate and construct confidence intervals for the value of Z corresponding to a given value of D. We describe the procedure in the context of a dose-response relationship, where it is desired to estimate the dose (Z) to effect a given amount of change (D), but the method is more general than this. In particular, it may be usefully applied in calibration problems where one may wish to estimate the true value of a measurement given the value as read from a measuring device.

authors

• Schneiderman, Emet

published proceedings

• Int J Biomed Comput

author list (cited authors)

• Kowalski, C. J., Schneiderman, E. D., & Willis, S. M.

citation count

• 0

complete list of authors

• Kowalski, CJ||Schneiderman, ED||Willis, SM

publication date

• January 1995

publisher

• Elsevier  Publisher

published in

• International journal of bio-medical computing  Journal

keywords

• Antimony
• Blood Pressure
• Calibration
• Computer Simulation
• Confidence Intervals
• Dose-Response Relationship, Drug
• Drug Therapy, Computer-assisted
• Humans
• Microcomputers
• Regression Analysis
• Software
• User-Computer Interface

Digital Object Identifier (DOI)

• 10.1016/s0020-7101(05)80005-4

start page

• 233

end page

• 238

volume

• 38

issue

• 3

URL

• http://dx.doi.org/10.1016/s0020-7101(05)80005-4