Novel approach to elucidate the nature of photomodulation therapy
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2017 SPIE. Photobiomodulation therapy has been around for several decades with a number of applications increasing every year. However, the exact mechanisms of energy/signal transduction, which lead to the observed changes, and the lack of those in living cells, is still poorly understood. We propose and experimentally implement a novel research platform, which uses a microfluidic chip and controllable excitation condition to precisely initiate the process of photobiomodulation. Resonance Raman spectroscopy is employed to assess the structural transformational stages on different time-scales. We will present our first experimental results and discuss those results with respect to potential therapeutic applications.