[Periodontal diagnosis based on an immunohistochemical-morphometric analysis].
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abstract
What is the correlation between immunoreactive blood cells, clinical parameters and the presence of special subclasses of bacteria in the subgingival microflora? To answer this question, patients suffering from juvenile and rapid progressive periodontitis were examined and compared with a control group without any periodontal disease. Cryostat sections from gingiva biopsies were marked immunohistochemically. Using the Kruskall-Wallis test, highly significant differences could be shown between the groups of disease in terms of immunoreactive cells such as leukocytes and monocytes, as well as in terms of the clinical parameters pocket depth, plaque index, gingival index and sulcus fluid and in terms of the microbiological subclasses coccoid cells, curved and motile rods and spirochetes. The results showed that immunohistochemical and morphometric methods of characterizing immunoreactive white blood cells might be used as an aid in diagnosis and understanding of periodontal diseases.
