Nerve Fiber Layer Infarcts in Thiamine Deficiency. Academic Article uri icon


  • Thiamine deficiency classically manifests as the triad of Wernicke encephalopathy: acute confusional state, ataxic gait, and ocular motor dysfunction. However, most patients do no present with this classic triad. Optic neuropathy in thiamine deficiency is a rare manifestation and is usually associated with fundus appearances of optic disc swelling or optic disc pallor. We present 2 unique cases of thiamine deficiency where the fundus demonstrated peripapillary retinal nerve fiber layer thickening without florid disc swelling or pallor.

published proceedings

  • J Neuroophthalmol

altmetric score

  • 0.5

author list (cited authors)

  • Sia, P. I., Sia, D., Crompton, J. L., & Casson, R. J.

citation count

  • 4

complete list of authors

  • Sia, Paul I||Sia, David IT||Crompton, John L||Casson, Robert J

publication date

  • September 2015