Effect of pseudomonas lipase enzyme on the degradation of polycaprolactone/polycaprolactone-polyglycolide fiber blended nanocomposites Academic Article uri icon


  • 2018, 2018 Taylor & Francis. This study describes the interaction resulting from adding pseudomonas lipase (PS) enzyme to polycaprolactone-based composites designed for orthopedic applications. The biopolymer composite evaluated in this study consists of electrospun polycaprolactone (PCL)/polyglycolide (PGA) blended fibers impregnated with double stranded deoxyribonucleic acid wrapped single-walled carbon nanotubes encapsulated by a PCL matrix. PS enzyme was used to catalyze the degradation of PCL-based biocomposites. PCL present in the biocomposites showed considerable degradation in 4 weeks in the presence of the enzyme, exhibiting a contrast to hydrolytic degradation which lasts several years. PGA-consisting fibers degraded completely within one week of exposure to the enzyme.

published proceedings

  • International Journal of Polymeric Materials and Polymeric Biomaterials

author list (cited authors)

  • Spearman, S. S., Irin, F., Ramesh, S., Rivero, I. V., Green, M. J., & Harrysson, O.

citation count

  • 8

complete list of authors

  • Spearman, Shayla S||Irin, Fahmida||Ramesh, Srikanthan||Rivero, Iris V||Green, Micah J||Harrysson, Ola LA

publication date

  • May 2019