Purification of an antibiotic effective against Gaeumannomyces graminis var. tritici produced by a biocontrol agent, Pseudomonas aureofaciens Academic Article uri icon


  • Inhibition of the fungus that causes take-all of wheat, Gaeumannomyces graminis (Sacc.) Arx and Oliver var. tritici Walker, by a biocontrol agent, Pseudomonas aureofaciens Q2-87, was demonstrated both in vitro and in vivo. Q2-87 was originally isolated from the rhizosphere of wheat grown in a take-all suppressive soil. An antifungal compound was isolated from a chemically-defined broth culture of strain Q2-87. The structure of the compound was established to be 1,3,6-trihydroxy-2,4-diacetophenone through infrared, [1H]nuclear magnetic resonance (NMR), [113C]NMR, u.v., and high-resolution fast-atom bombardment (FAB) mass spectrometry. The synthesized product of the proposed structure demonstrated activity equal to the purified natural product. 1993.

published proceedings

  • Soil Biology and Biochemistry

altmetric score

  • 3

author list (cited authors)

  • Harrison, L. A., Letendre, L., Kovacevich, P., Pierson, E., & Weller, D.

citation count

  • 82

complete list of authors

  • Harrison, Leslie A||Letendre, Leo||Kovacevich, Peter||Pierson, Elizabeth||Weller, David

publication date

  • February 1993