Amino acid concentrations in the Aplysia nervous system: neurons with high glycine concentrations. Academic Article uri icon

abstract

  • Abstract The levels of the amino acids glycine, aspartic acid and glutamic acid were determined in the ganglia and in identified neurons of A. californica. All of the determinations were done by gas chromatographymass spectrometryselected ion monitoring using deuteriumlabelled amino acids as internal standards. Aspartate and glutamate concentrations vary 2 to 3fold among the ganglia and individual neurons. Glycine levels are 310 times higher in the abdominal ganglion than in the other ganglia. This is in large part due to the glycine concentrations in the abdominal ganglion neurons R3R14 being about 20 times higher than in the somata of most other Aplysia neurons. The concentrations of all three amino acids are several times lower in the muscle than in ganglia, and orders of magnitude lower in the hemolymph than in tissue. Copyright 1977, Wiley Blackwell. All rights reserved

published proceedings

  • J Neurochem

author list (cited authors)

  • Iliffe, T. M., McAdoo, D. J., Beyer, C. B., & Haber, B.

citation count

  • 43

complete list of authors

  • Iliffe, TM||McAdoo, DJ||Beyer, CB||Haber, B

publication date

  • May 1977

publisher