Monoclonal antibody manufacturing in transgenic plants--myths and realities.

abstract

• The number and types of antibodies expressed in plants has increased steadily since the first reports of this accomplishment in the 1980s, illustrating the versatility of plants as a production system for antibodies. Many recent reviews have detailed the antibody forms that have been derived from plant expression systems. This contribution focuses on the remaining challenges to develop plant-derived therapeutic antibodies into products, and some of the progress that is being made in addressing these challenges.

authors

• Woodard, Susan

published proceedings

• Curr Opin Biotechnol

altmetric score

• 6

author list (cited authors)

• Hood, E. E., Woodard, S. L., & Horn, M. E.

citation count

• 131

complete list of authors

• Hood, Elizabeth E||Woodard, Susan L||Horn, Michael E

publication date

• January 2002

publisher

• Elsevier  Publisher

published in

• Current Opinion in Biotechnology  Journal

keywords

• Antibodies, Monoclonal
• Drug Industry
• Gene Expression Regulation, Plant
• Glycolysis
• Plants, Genetically Modified
• Seeds
• Truth Disclosure
• Zea Mays

Digital Object Identifier (DOI)

• 10.1016/s0958-1669(02)00351-8

start page

• 630

end page

• 635

volume

• 13

issue

• 6

URL

• http://dx.doi.org/10.1016/s0958-1669(02)00351-8