Monoclonal antibody manufacturing in transgenic plants — myths and realities
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The number and types of antibodies expressed in plants has increased steadily since the first reports of this accomplishment in the 1980s, illustrating the versatility of plants as a production system for antibodies. Many recent reviews have detailed the antibody forms that have been derived from plant expression systems. This contribution focuses on the remaining challenges to develop plant-derived therapeutic antibodies into products, and some of the progress that is being made in addressing these challenges.
author list (cited authors)
Hood, E. E., Woodard, S. L., & Horn, M. E.