Shell cross-linked knedels: Amphiphilic core-shell nanospheres and their potential applications
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abstract
The shell-crosslinked knedels (SCK) are polymer micelles containing covalent crosslinks that serve to reinforce the micellar architecture. The SCKs are water soluble due to the hydrophilic, quaternized poly(4-vinylpyridine) shell and should provide additional free volume in the non-crosslinked, polystyrene core for uptake or encapsulation of small molecules. This allows the SCKs to be envisioned for a variety of applications including drug delivery, gene therapy, encapsulation technologies, as well as non-biological applications such as water treatment, coatings, and inks.