Meta-Analysis of QTL Associated with Fusarium Head Blight Resistance in Wheat
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Quantitative trait loci (QTL) associated with resistance to Fusarium head blight (FHB), which is mainly caused by Fusarium graminearum Schwabe [telomorph: Gibberella zeae Schw. (Petch)], have been identifi ed in wheat (Triticum aestivum L.) from different countries. Due to the differences of genetic backgrounds and analysis methods, the linked marker and signifi cance levels of QTL are not consistent across studies. Such discrepancies make it diffi cult to select diagnostic fl anking markers. Meta-analysis has been used to estimate the confi dence intervals (CIs) of QTL in plant and animal genomes. The objective of this study was to cluster 249 FHB resistance QTL identifi ed in 46 unique lines from 45 studies based on the estimated QTL CI by meta-analysis. A total of 209 QTL conditioning FHB resistance type I, II, III and IV were classifi ed into 43 clusters on 21 chromosomes. Among them, 119 QTL were signifi cant and 116 QTL explained more than 10% of phenotypic variation. There are 19 confi rmed QTL located on chromosomes 3A, 5A, 7A, 1B, 3BS, 5B, 6B, and 2D. The results provide chromosome locations and linked markers for overlapping and unique QTL. Markers fl anking QTL clusters can be used to pyramid diverse QTL more effi ciently through marker-assisted breeding. Crop Science Society of America.