Hypothalamic-pituitary-adrenal axis dysfunction in non-clinical psychosis.
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abstract
While studies have examined psychosocial stress in non-clinical psychosis (NCP), it is unclear if the elevated cortisol seen in schizophrenia also occurs in this group. Cortisol was sampled in High- and Low-NCP groups, and findings of elevated resting cortisol in the former suggest that hypothalamic-pituitary-adrenal-axis dysfunction underlies a psychosis continuum. Copyright 2012 Elsevier Ireland Ltd. All rights reserved.