Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles. Academic Article uri icon

abstract

  • We fabricated a microfluidic device consisting of ciliated micropillars, forming a porous silicon nanowire-on-micropillar structure. We demonstrated that the prototype device can preferentially trap exosome-like lipid vesicles, while simultaneously filtering out proteins and cell debris. Trapped lipid vesicles can be recovered intact by dissolving the porous nanowires in PBS buffer.

published proceedings

  • Lab Chip

altmetric score

  • 3

author list (cited authors)

  • Wang, Z., Wu, H., Fine, D., Schmulen, J., Hu, Y. e., Godin, B., Zhang, J., & Liu, X.

citation count

  • 225

complete list of authors

  • Wang, Zongxing||Wu, Hung-jen||Fine, Daniel||Schmulen, Jeffrey||Hu, Ye||Godin, Biana||Zhang, John XJ||Liu, Xuewu

publication date

  • August 2013