Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles Academic Article uri icon

abstract

  • We fabricated a microfluidic device consisting of ciliated micropillars, forming a porous silicon nanowire-on-micropillar structure. We demonstrated that the prototype device can preferentially trap exosome-like lipid vesicles, while simultaneously filtering out proteins and cell debris. Trapped lipid vesicles can be recovered intact by dissolving the porous nanowires in PBS buffer.

altmetric score

  • 3

author list (cited authors)

  • Wang, Z., Wu, H., Fine, D., Schmulen, J., Hu, Y. e., Godin, B., Zhang, J., & Liu, X.

citation count

  • 177

publication date

  • January 2013