ENDOR of metalloenzymes. Academic Article uri icon


  • This Account examines the role of electron-nuclear double resonance (endor) spectroscopy in furthering our understanding of how metal ions function in biological systems. It briefly describes endor and electron spin-echo envelope modulation (eseem) spectroscopies and then illustrates the uses of endor with several case studies from our own research: cytochrome c peroxidase compound ES; ribonucleotide reductase intermediate X; allylbenzene-inactivated chloroperoxidase; the role of the [4Fe-4S](+) cluster in enzymes of the "radical S-adenosylmethionine" superfamily; dioxygen activation by heme enzymes. Finally, it briefly considers future developments.

published proceedings

  • Acc Chem Res

altmetric score

  • 3

author list (cited authors)

  • Hoffman, B. M.

citation count

  • 74

complete list of authors

  • Hoffman, Brian M

publication date

  • July 2003