IMPROVED AUTOMATIC CENTERLINE TRACING FOR DENDRITIC STRUCTURES
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Centerline tracing of dendritic structures in confocal images of neurons is an essential tool for the construction of a geometric representation of a neuronal network. In this paper, we propose a novel algorithm (ORION 2) for centerline extraction that is both highly accurate and computationally efficient. The main novelty of the proposed method is the use of a small set of Multiscale Isotropic Laplacian filters for a fast and efficient binarization of the dendritic structure. The performance of this algorithm, which is validated using datasets from DIADEM is shown to be very competitive against other state-of-the-art algorithms. © 2013 IEEE.
author list (cited authors)
Jiménez, D., Papadakis, M., Labate, D., & Kakadiaris, l. A.