Retinoic acid receptor transcripts in human umbilical vein endothelial cells.
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abstract
Human umbilical vein endothelial cells contain high levels of mRNA for the beta-retinoic acid receptor, and very low levels of alpha-retinoic acid receptor transcripts. The cells responded to retinoic acid with a significant induction of tissue transglutaminase expression but no alterations in the expression of beta-retinoic acid receptor transcripts. The physiological implications of the constitutive expression of this receptor in endothelial cells is discussed.