Surface-Enhanced Raman Spectroscopy Biosensing: In Vivo Diagnostics and Multimodal Imaging. Academic Article

abstract

• This perspective presents recent developments in the application of surface-enhanced Raman spectroscopy (SERS) to biosensing, with a focus on in vivo diagnostics. We describe the concepts and methodologies developed to date and the target analytes that can be detected. We also discuss how SERS has evolved from a "point-and-shoot" stand-alone technique in an analytical chemistry laboratory to an integrated quantitative analytical tool for multimodal imaging diagnostics. Finally, we offer a guide to the future of SERS in the context of clinical diagnostics.

authors

• Kurouski, Dzmitry

published proceedings

• Anal Chem

altmetric score

• 2.85

author list (cited authors)

• Henry, A., Sharma, B., Cardinal, M. F., Kurouski, D., & Van Duyne, R. P.

citation count

• 191

complete list of authors

• Henry, Anne-Isabelle||Sharma, Bhavya||Cardinal, M Fernanda||Kurouski, Dmitry||Van Duyne, Richard P

publication date

• July 2016

publisher

• American Chemical Society (ACS)  Publisher

published in

• Analytical Chemistry  Journal

keywords

• Animals
• Antibodies
• Antineoplastic Agents
• Biomarkers
• Biosensing Techniques
• Doxorubicin
• Fluorescent Dyes
• Humans
• Mice
• Mice, Nude
• Microscopy, Confocal
• Multimodal Imaging
• Nanoparticles
• Neoplasms
• Spectrum Analysis, Raman

PubMed Central ID

• 27268724

Digital Object Identifier (DOI)

• 10.1021/acs.analchem.6b01597

start page

• 6638

end page

• 6647

volume

• 88

issue

• 13

URL

• http://dx.doi.org/10.1021/acs.analchem.6b01597