Surface-Enhanced Raman Spectroscopy Biosensing: In Vivo Diagnostics and Multimodal Imaging. Academic Article uri icon


  • This perspective presents recent developments in the application of surface-enhanced Raman spectroscopy (SERS) to biosensing, with a focus on in vivo diagnostics. We describe the concepts and methodologies developed to date and the target analytes that can be detected. We also discuss how SERS has evolved from a "point-and-shoot" stand-alone technique in an analytical chemistry laboratory to an integrated quantitative analytical tool for multimodal imaging diagnostics. Finally, we offer a guide to the future of SERS in the context of clinical diagnostics.

published proceedings

  • Anal Chem

altmetric score

  • 3.2

author list (cited authors)

  • Henry, A., Sharma, B., Cardinal, M. F., Kurouski, D., & Van Duyne, R. P.

citation count

  • 161

complete list of authors

  • Henry, Anne-Isabelle||Sharma, Bhavya||Cardinal, M Fernanda||Kurouski, Dmitry||Van Duyne, Richard P

publication date

  • July 2016